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• Pain relief.
• Relief of respiratory distress and reduction of preload in pulmonary edema.
• For analgesia, as an adjunct to sedation in the intubated patient.
• Patients with known hypersensitivity to morphine or other opioids.
• Hypotension that has not been treated.
• Acute or severe bronchial asthma or other obstructive airways disease, prior
• Severe liver disease or incipient hepatic encephalopathy.
• Biliary colic, biliary tract surgery, GIT obstruction.
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• Morphine is an agonist at all opioid receptors particularly the mu receptor.
• It binds to mu receptors in the brain, spinal cord and other organs containing smooth muscle.
• Morphine produces many effects including analgesia, decreased gastrointestinal motility, respiratory depression, drowsiness, changes in mood and alterations of the endocrine and autonomic nervous systems.
• Nausea and vomiting may occur through direct stimulation of the chemoreceptor trigger zone. Urinary retention may occur due to increased bladder sphincter tone.
• It is distributed throughout the body but most especially to the kidney, lung, liver, and spleen.
• When given as an IV bolus, morphine acts within 2 minutes, peaks at 20 minutes and lasts for up to hours.
Morphine Is Potential In Treating Moderate To Severe Pain, With The Long-lasting Effects.
• Tell Your Doctor About Your Previous And Currents Allergies.
• During Pregnancy, It Is Recommended To Not To Use Opioid, As It May Harm Unborn Baby.
• Uncoordinated Movement.
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